New Amsterdam Genomics

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Discovering what's in your DNA can unlock new opportunities to improve and optimize your health. Start today!

Individual in Focus

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New Amsterdam Genomics is powerful insightful life-changing

We predict that by 2020, 20% of Americans will know their DNA. DNA sequencing will transform how people stay healthy. People will not have to react to symptoms; they will proactively prevent problems their DNA predisposes them to.

N.A.G. brings this "precision medicine" to life. We have created the world's premier DNA test, scanning all 22,000 genes of your DNA and cross-referencing them with more than 100,000 health-related findings. Whether you are healthy or sick, our test can potentially teach you valuable things about your health.

What Can I Learn From This Test?

Am I at risk of a serious medical condition such as heart disease, diabetes, or cancer?
How can I tailor my diet, exercise, and lifestyle choices to optimize my health?
Which medicines and therapies are safest and most effective for me?

Specific Examples

We have identified which cancers people are at highest risk for, based on their DNA. This is an amazing advancement: even just a few years ago, science knew very little about what caused people without risky lifestyles (such as smoking) to develop cancer. Our information can direct the type of screening a person receives, meaning cancer may be caught earlier and may be easier to treat.
There are three main types of cardiac problems: Heart Arrhythmias, Structural Heart Disease, and Coronary Heart Disease. We check for genetic risks for all three. For example, we have identified patients who have rare cardiac defects. This is extraordinary; these people may have been at risk for effects as serious as sudden cardiac death, but with help from a cardiologist, they can potentially avoid this fate and live longer.
We have identified numerous rare diseases in patients. Examples of rare diseases include Tuberous sclerosis, Waardenburg syndrome, Peutz Jeghers syndrome, and Hypertrophic Obstructive Cardiomyopathy. Approximately 10% of Americans have a rare disease, and most rare diseases are not immediately life threatening, so we feel you should not fear learning you might have one. Knowing that you have something rare can answer a lot of questions about your health. For example, it may explain symptoms you may have. It can also help your doctors manage your health better. Doctors could manage your symptoms in different ways, possibly provide more effective mitigation therapies, and possibly create a surveillance plan against the disease's most significant effects.
We can find the genetic basis of all sorts of chronic diseases including diabetes, asthma, eczema, multiple sclerosis, and more. (However, genetics does not cause every disease; sometimes these diseases are caused by a person's lifestyle or simply bad luck.)
Some people are interested in learning if they are at risk for dementia as they age. We have helped many people determine their risk. In a few cases, we have been able to propose possible mitigation steps. Neurodegenerative problems, such as Parkinson's disease, is another question many people have about their health.
The genes in the Cytochrome P450 complex have some of the strongest impacts on why certain medications work differently in some people as compared to others. (Click here for a Wikipedia article on Cytochrome P450.) We analyze these genes plus many others to predict which medicines will work best for each person. We can even in some cases determine ideal dosages for medicines.
Have you ever wondered why certain diets work better for some people than others? There is exciting research going on right now that compares how people perform on different diets, based on variations in their DNA. We have used these studies to recommend specific diets for people. A few options include the saturated fat diet (similar to Atkins); the monounsaturated fat diet (Mediterranean diet); and the high carbohydrate, low fat diet.
There are two neat aspects to our fitness recommendations. First, we can show you how different exercises affect your body in unique ways. For instance, we have results that say aerobic exercise may be more or less likely to improve your insulin sensitivity or more or less likely to improve your HDL (good cholesterol). The second neat aspect is that we can show you which types of fitness you are more likely to excel in. This can help you become a better athlete, if you are so inclined.
The average person carries multiple diseases in their DNA that they do not express themselves. Such diseases are called "recessive." These are not problems unless the person and their partner both carry the same recessive disease; in that case, the couple's children are at risk of becoming afflicted with that disease. Examples of recessive diseases include Cystic Fibrosis, Tay-Sachs disease, Familial Mediterranean fever, and Niemann-Pick disease. Recessive diseases can often be debilitating, so you really don't want your child to be afflicted. Therefore, even if you and your partner are completely healthy, it still can be a very good idea to check which recessive diseases you carry. To learn more about recessive diseases, here the US government has written a great explanation here.
Ancestry determination is included with our analysis. We compare your DNA with 52 different populations from around the globe. Which region of the world do your ancestors come from?

The N.A.G. Difference

Whole Exome Sequencing

We analyze all 22,000 of your genes. Older tests, such as 23andMe, did what is called genotyping, which is looking at your DNA in just a few discrete places. Our approach provides a much broader view of your genome, and can even reveal rare mutations you may have.

Major Impacts

Earlier DNA tests generally only produced medical findings with small effect sizes (e.g. a 5% increased risk of something or a 10% decreased risk of something). We argue that these small findings are not very useful, because they probably would not change how you and your doctor manage your health. N.A.G., by contrast, routinely finds medical issues that people are multiple times higher risk for. The reason is that we are able to measure and make sense of very rare mutations.

Advanced Computer Analysis

N.A.G. was founded on the premise that analyzing billions of DNA measurements, as is done in large scale genomics, requires elite computer programming to be done right. We have some of the best programmers in the world, and they have created superior algorithms to analyze your DNA.

Comprehensive

We report on everything from significant medical findings to diet and exercise recommendations to ancestry. We report anything we can find about your DNA, so long as there is a peer-reviewed, published paper to back it up.

child after DNA analysis

Recommended by the Best

We are honored that some of the best doctors in the country have endorsed us:

New Amsterdam Genomics exome sequencing is the beginning of the future standard in which patients will have a genetic blueprint to help guide them and their physicians in day to day choices as well as customized plans for the prevention of illness.

Dr. Dirk FraterE. Barrow Medical Group -- Dallas, TX

Patients are empowered to become more engaged in their health and their future when they have the level of information that is available through genomic testing with NAG.

Dr. Edward S. GoldbergConcierge MD

This is one of the best preventive and discovery tools I have at my disposal today.

Dr. Thom LobeRegeneveda -- Chicago, IL

Get Started

It's easy to get sequenced by New Amsterdam Genomics.

  1. Enter your contact information in the box below.
  2. Ask your doctor about our test. We can send you materials to show your doctor. Don't have a doctor? No problem. We will connect you with a great one in our network.
  3. We send a kit to your home with all the materials you need. Collect your saliva, and ship the kit back to us.
  4. DNA is extracted from your specimen, and the sequence (a list of A's, C's, G's, and T's) is determined over the entire protein coding region of your genome. N.A.G. runs sophisticated algorithms on your data to uncover meaning and impact.
  5. N.A.G. delivers to your doctor a report explaining your unique genomic findings. You receive access to an online portal enabling you to investigate your results at every level of detail. With your genome decoded, your doctor and you can devise ways to optimize your health.

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